国际眼科纵览 ›› 2020, Vol. 44 ›› Issue (5): 346-350.doi: 10.3760/ cma.j.issn.1673-5803.2020.05.009

• 综述 • 上一篇    下一篇

Ozurdex治疗眼后段疾病引起的黄斑水肿

谭丛 秦梅   

  1. 蚌埠医学院第一附属医院眼科,安徽蚌埠233000
  • 收稿日期:2020-04-07 出版日期:2020-10-22 发布日期:2020-11-01
  • 通讯作者: 秦梅,Email:bbmcqm@163.com

Ozurdex in the treatment of macular edema caused by posterior ophthalmic diseases

Tan Cong, Qin Mei   

  1. Department of Ophthalmology, the First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233000, China
  • Received:2020-04-07 Online:2020-10-22 Published:2020-11-01
  • Contact: Qin Mei, Email: bbmcqm@163.com

摘要:

黄斑水肿是眼底病患者视功能减退的主要原因之一。多种因素造成血-视网膜屏障的破坏,形成黄斑水肿,其中炎性反应在形成黄斑水肿中发挥着重要作用。为克服传统玻璃体内注射糖皮质激素的局限性,具有良好的临床效果、独特的药物缓释系统的地塞米松玻璃体内植入剂Ozurdex为黄斑水肿治疗提供新的选择,其在治疗视网膜静脉阻塞、糖尿病视网膜病变、非感染性葡萄膜炎等眼底疾病继发的黄斑水肿有良好的疗效和安全性。(国际眼科纵览,2020, 44:346-350)

关键词: Ozurdex, 黄斑水肿, 视网膜静脉阻塞, 糖尿病性黄斑水肿, 非感染性葡萄膜炎

Abstract:

Macular edema is one of the main causes of visual dysfunction in patients with fundus disease. Many factors cause the destruction of blood-retinal barrier and form macular edema, among which inflammation plays an important role in the formation of macular edema. In order to overcome the limitations of traditional intravitreous hormone injection, dexamethasone vitreous implant (Ozurdex) came into being. Its good clinical effect and unique drug delivery system provide a new choice for the treatment of macular edema. Ozurdex has good efficacy and safety in the theatment of macular edema caused by fundus diseases such as retinal vein occlusion, diabetic retinopathy and non-infective uveitis.(Int Rev Ophthalmol, 2020, 44:346-350)

Key words: Ozurdex, macular edema, retinal vein occlusion, diabetic macular edema, noninfectious uveitis